Place of Origin | China |
Brand Name | Firsky |
Model Number | FS-CAS 4759-48-2 |
Document | Product Brochure PDF |
Product Description
Product Name: | Isotretinoin |
Synonyms: | Tretinoin Impurity 1(Tretinoin EP Impurity A);Anti Acne Powerful Isotretinoin Powder Isotretinoin Pharmaceutical Raw Materials;Isotretinoin Capsules;Isotretinoin-D5/13-cis-Retinoic acid-D5;Roaccutan;(2Z,4E,6E,8E)-3,7-diMethyl-9-(2,6,6-triMethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid;ISOTRETINON;A different diMension acid |
CAS: | 4759-48-2 |
MF: | C20H28O2 |
MW: | 300.44 |
EINECS: | 225-296-0 |
Melting point | 172-175 °C (lit.) |
Boiling point | 381.66°C (rough estimate) |
density | 1.0597 (rough estimate) |
refractive index | 1.4800 (estimate) |
storage temp. | -20°C |
solubility |
Practically insoluble in water, soluble in methylene chloride, slightly soluble in ethanol (96 per cent). It is sensitive to air, heat and light, especially in solution. Carry out all operations as rapidly as possible and avoid exposure to actinic light; use freshly prepared solutions. |
pka | 4.76±0.33(Predicted) |
form | Fine Crystalline Powder |
color | Yellow-orange to orange |
Description
The CAS number 4759-48-2 corresponds to isotretinoin in the Chemical Abstracts Service registry. Isotretinoin is a medication that is primarily used for the treatment of severe acne that has not responded to other treatments. It is a derivative of vitamin A and belongs to a class of drugs known as retinoids.
Here is a description of isotretinoin and its properties:
Acne Treatment: Isotretinoin is highly effective in treating severe, nodular acne that has not responded to other treatments. It works by reducing the size of sebaceous glands and decreasing sebum (oil) production in the skin. By reducing oil production and preventing the clogging of pores, isotretinoin helps to minimize acne breakouts and improve the overall appearance of the skin.
Sebum Regulation: Isotretinoin helps to regulate the production of sebum, which is an oily substance produced by the sebaceous glands. Excessive sebum production can contribute to the development of acne. By reducing sebum production, isotretinoin helps to control oiliness and prevent blockage of hair follicles.
Anti-inflammatory Effects: Isotretinoin has anti-inflammatory properties, which can help reduce redness, swelling, and inflammation associated with acne breakouts. It helps to calm the skin and promote a clearer complexion.
Impact on Keratinization: Isotretinoin can normalize the process of keratinization, which is the formation and shedding of skin cells. It helps to prevent the accumulation of dead skin cells within the follicles, reducing the formation of comedones (clogged pores) and promoting smoother skin texture.
Potential Side Effects: Isotretinoin is a potent medication and can have significant side effects. Some common side effects include dryness of the skin, lips, and eyes, as well as increased sensitivity to sunlight. It may also cause dryness of the nasal passages, nosebleeds, and muscle or joint pain. Isotretinoin can cause birth defects if taken during pregnancy, so it is important to follow strict guidelines and use reliable contraception methods while taking this medication.
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