Cas 19130-96-2 1-Deoxynojirimycin D-5-Amino-1,5-dideoxyglucopyranose desoxynojirimycin 1-Deoxy-Nojirimycin

Product Description

Description

CAS number 19130-96-2 corresponds to a compound called 1-deoxynojirimycin (DNJ). DNJ is a naturally occurring iminosugar found in various plants, including mulberry leaves. It has gained significant attention due to its potential therapeutic applications.

DNJ possesses inhibitory properties against certain enzymes, particularly α-glucosidases. These enzymes are responsible for breaking down complex carbohydrates into simpler sugars during digestion. By inhibiting α-glucosidases, DNJ can slow down the absorption of glucose in the small intestine, leading to reduced postprandial (after-meal) blood glucose levels.

Due to its ability to modulate carbohydrate metabolism, DNJ has been investigated for its potential use in managing diabetes and related conditions. It has been studied for its hypoglycemic (blood sugar-lowering) effects and its ability to improve insulin sensitivity.

Application

CAS number 19130-96-2 corresponds to 1-deoxynojirimycin (DNJ), a compound with several potential applications. Here are some of the notable applications of DNJ:

Anti-diabetic agent: DNJ has gained attention for its ability to inhibit α-glucosidases, enzymes involved in carbohydrate digestion. By slowing down the absorption of glucose in the small intestine, DNJ can help regulate blood sugar levels. It has been studied for its potential use in managing diabetes and improving insulin sensitivity.

Glycosidase inhibitor: DNJ acts as an inhibitor of various glycosidase enzymes, including α-glucosidases and α-galactosidases. These enzymes are involved in the breakdown of complex carbohydrates and glycoproteins. DNJ's inhibitory activity makes it useful in studying and modulating carbohydrate metabolism.

Antiviral agent: DNJ has demonstrated antiviral activity against certain viruses, including human immunodeficiency virus (HIV). It interferes with the processing of viral glycoproteins, inhibiting viral replication. DNJ's antiviral potential has been investigated for the development of novel therapeutic strategies.

Antitumor agent: Preclinical studies have shown that DNJ possesses anticancer properties. It has been found to inhibit tumor cell growth, induce apoptosis (programmed cell death), and suppress metastasis. DNJ's potential as an antitumor agent holds promise for future research and development in cancer treatment.

Neuroprotective effects: DNJ has been studied for its neuroprotective properties. It has shown the ability to protect neurons from oxidative stress, prevent neuroinflammation, and exhibit neurotrophic effects. These findings suggest that DNJ may have potential applications in neurodegenerative disorders and brain health.

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