Specifications:

Description:

N-Acetylneuraminic acid, CAS 131-48-6, is a high-value bioactive derivative of sialic acid with diverse applications in medicine, pharmacology, and biotechnology. Below is a detailed product description of this extraordinary molecule:

N-acetylneuraminic acid (Neu5Ac) is an important component of gangliosides, a type of glycolipid found in eukaryotic cell membranes that play an important role in cell recognition, signal transduction and membrane fluidity. effect. The molecular formula of Neu5Ac is C11H19NO9 and the molecular weight is 291.268. It is a white to yellow crystalline powder that is easily soluble in water and polar organic solvents.

N-acetylneuraminic acid has been widely used in biomedicine as a research tool to study the function and structure of cell membrane gangliosides. It has also been used as a starting material for the synthesis of various ganglioside analogs with potential applications in the treatment of neurodegenerative diseases and cancer.

In addition to its use in the research and synthesis of ganglioside analogs, Neu5Ac is also used as a reaction intermediate in the preparation of various glycoconjugates. Glycoconjugates are molecules containing carbohydrate moieties linked to other biologically active molecules such as proteins, lipids, and nucleic acids. These complex sugars play crucial roles in cell-to-cell recognition, signaling, and immune responses.

Application:

N-acetylneuraminic acid (CAS 131-48-6) has a wide range of applications in different fields, including medicine, pharmacology and biotechnology. Here are some specific applications of N-acetylneuraminic acid:

1. Biomedicine and research: As an important component of gangliosides, N-acetylneuraminic acid is used as a biomedical research tool to study the function and structure of gangliosides in cell membranes. It is also a starting material for the synthesis of ganglioside analogs with potential applications in the treatment of neurodegenerative diseases and cancer.

2. Glycobiology: In addition to its use in research and ganglioside analog synthesis, Neu5Ac is also used as a reaction intermediate in the preparation of various glycoconjugates. Glycoconjugates are molecules containing carbohydrate moieties linked to other biologically active molecules such as proteins, lipids, and nucleic acids. These complex sugars play crucial roles in cell-to-cell recognition, signaling, and immune responses.

3. Pharmacology and therapeutics: N-acetylneuraminic acid has been shown to have antiviral activity against influenza viruses. It is thought to interfere with viral binding to host cells by competing with the virus for binding sites on gangliosides.

4. Biotechnology: Neu5Ac can also be used in biotechnology, such as the development of vaccines and diagnostics. It acts as a ligand for ganglioside receptors on cells, helping to target drugs or therapeutics to specific cells or tissues.

5. Cosmetics: N-acetylneuraminic acid is also used in cosmetics as a skin conditioner and moisturizer. It is added to personal care products to improve skin softness and moisture levels.

Advantage:

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FAQ:

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