2023-09-20
2-Bromo-1-phenyl-1-butanone CAS 1451-83-8 is an important intermediate in the synthesis of many drugs and pesticides. It is a colorless or white solid at room temperature and has a molecular formula of C10H11BrO.
2-Bromo-1-phenyl-1-butanone CAS 1451-83-8 can be prepared by bromination of phenylbutanone in the presence of catalysts such as iron bromide or aluminum bromide. The bromination reaction is carried out at a temperature of about 80°C and pressure of about 20 atmospheres. The catalyst is filtered off and the crude product is washed with water to remove unreacted phenylbutanone and bromide salts.
2-Bromo-1-phenyl-1-butanone CAS 1451-83-8 is a solid at room temperature with a melting point between 45°C and 47°C. It is insoluble in water but soluble in organic solvents such as alcohols, esters, and ethers.
2-Bromo-1-phenyl-1-butanone CAS 1451-83 -8 is an intermediate in the synthesis of many drugs and pesticides. It can be used to prepare insecticides such as pyrethroids and flumethrin. It can also be used to synthesize nonsteroidal anti-inflammatory drugs such as ibuprofen and mefenamic acid. Additionally, it can be used as an intermediate in the synthesis of other organic compounds.
2-Bromo-1-phenyl-1-butanone CAS 1451 should be stored in a tightly sealed container away from moisture and oxygen. It should not be stored together with acids, bases, or reducing agents. It should be handled with care because it is a lachrymator and skin irritant.
In conclusion, 2-bromo-1-phenyl-1-butanone CAS 1451-83-8 is an important intermediate in the synthesis of drugs and pesticides. It can be prepared by bromination of phenylbutanone and has useful properties that facilitate its handling and storage. It is used to prepare a variety of compounds including insecticides and nonsteroidal anti-inflammatory drugs. It should be handled with care because it is a lachrymator and skin irritant.
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